Global 3D Cell Culture Market Research Analysis 2021| Key Profiles, Global Industry Analysis, Outllok Report | Thermo Fisher Scientific, Inc., Merck KGaA, PromoCell GmbH
Global 3D Cell Culture Market
3D Cell Culture is defined
as a practice of growing biological cells and allow them to interact with their
surroundings in all three dimensions. This technique enables the cells to grow
in their natural environment in an in vivo condition. Numerous techniques are
used to carry out culturing of cells in all the three dimensions. 3-dimension
cell culture is a man-made environment. Cells grown in 3-dimension cell culture
with similar properties of cells found inside living organisms in terms of
cellular characteristics & behavior.
As three-dimension cell
cultures can mimic the structure, activity, as well as microenvironment of the
in-vivo tissues, this technique has varied applications in the fields of
regenerative medicine, drug screening, stem cell therapies, cancer research
& cell biology. The extracellular matrix in three-dimension cell cultures
alows cell–cell communication by direct contact as in in-vivo environment by
secreting cytokines & trophic factors. These factors are changed in a 2D
environment which can significantly affect the cell–cell communication, which
in turn can alter the cell morphology & proliferation. As 2-Dimesion
cultures cannot recapitulate the architecture & complex cellular matrices
as in 3-Dimension cultures, this technique is gaining popularity in healthcare
research industry. Also, 3D cell cultures can offer results with improved
efficiency & reduce the cost of overall research and development process.
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The cancer and stem cell
segment is anticipated to grow at the highest CAGR over the forecast period.
On the basis of application, the 3D cell culture market is categorized
into drug discovery & toxicology testing, cancer & stem cell research,
and tissue engineering & regenerative medicine. The cancer and stem cell
research segment hold the largest revenue share of the market and is projected
to register the highest CAGR during this forecast period. The increase in
prevalence of cancer and significant funding for cancer research are major
prominent factors driving the growth of this application segment.
Lack of consistency in
products is anticipated hamper growth of the global 3D cell culture market. The
lack of consistency between wells & batches of cell culture are the other
major challenges in the adoption of 3D cell culture. In addition, matrices made
from animal tissues may contain unwanted growth factors & viruses, which
could negatively affect the cell culture productivity &reproducibility.
Impact of COVID-19
The COVID-19 crisis has
resulted in nationwide lockdowns, thereby impacting every industry, Likewise,
market is also affected by the pandemic. The 3D cell culture industry is facing
various challenges to cope up with the demand & supply of 3D cell culture
components due to the COVID-19 crisis. Furthermore, inconsistent
&interrupted supply chain activities and availability of human resources
are projected to impact the market growth. Moreover, surge in research
practices for developing novel therapies against COVID-19 (Coronavirus) is
serving as a huge opportunity for the key market players. Research associated
with stem cell therapies and regenerative medicine has shown promising results
for treating the COVID-19, this is anticipated to compensate the deleterious
impact caused by lockdowns across the globe. Thus, the overall COVID-19 impact
is expected to remain moderate for the prominent players in the global 3D cell
culture market.
Market Segmentation
The Global 3D Cell Culture
Market is categorized into product including Scaffold-based 3D Cell Cultures,
(Solid Scaffolds, Hydrogels/ECM Analogs, and Micropatterned Surfaces),
Scaffold-free 3D Cell Cultures (Low Attachment Plates, Hanging Drop Plates, 3D
Bioreactors, 3D Petri Dishes), Microfluidics-based 3D Cell Cultures , and
Magnetic & Bioprinted 3D Cell Cultures, by application market is segmented
into Cancer & Stem Cell Research, Drug Discovery & Toxicology Testing,
and Tissue Engineering & Regenerative Medicine. Further, market is
segmented into end user such as Pharmaceutical & Biotechnology Companies,
Research Institutes, Cosmetics Industry, and Others.
Also, the Global 3D Cell
Culture Market is segmented into five regions such as North America,
Latin America, Europe, Asia Pacific, and Middle East & Africa.
Regional Analysis
North America led the
market share in the year 2020 & accounted for the highest revenue share
throughout the forecast period. Due to availability of private & government
funding for the development of advanced 3D cell culture models, high healthcare
spending, and the presence of a large number of universities & research
organizations investigating various stem cell-based approaches. For instance,
in December 2020, researchers from Mayo Clinic & Terasaki Institute, U.S.,
had developed visible hydrogels which can be used for the monitoring &
control of hemorrhage. However, the Asia Pacific region is estimated to be the
fastest-growing market due to the increase investments by various international
companies in the emerging economies of this region.
Market Key Players
Various key players are
listed in this report such as Thermo Fisher Scientific, Inc., Merck KGaA,
PromoCell GmbH, Corning, Inc., Greiner Bio One International GmbH, 3D
Biomatrix, Lonza, Tecan Trading AG, 3D Biotek
LLC, Global Cell Solutions, Inc., InSphero, etc.
Market Taxonomy
By Product
- Scaffold-based 3D Cell
Cultures
- Hydrogels/ECM Analogs
- Solid Scaffolds
- Micropatterned Surfaces
- Scaffold-free 3D Cell
Cultures
- Low Attachment Plates
- Hanging Drop Plates
- 3D Bioreactors
- 3D Petri Dishes
- Microfluidics-based 3D
Cell Cultures
- Magnetic & Bioprinted
3D Cell Cultures
By Application
- Cancer & Stem Cell
Research
- Drug Discovery &
Toxicology Testing
- Tissue Engineering &
Regenerative Medicine
By End User
- Pharmaceutical &
Biotechnology Companies
- Research Institutes
- Cosmetics Industry
- Others
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